"To be quiet and do as you're told, that's the cowardly choice." These are the words of Junk Dog, an underground fighter of Megalo Box, an evolution of boxing that utilizes mechanical limbs known as Gear to enhance the speed and power of its users. Despite the young man's brimming potential as a boxer, the illegal nature of his participation forces him to make a living off of throwing matches as dictated by his boss Gansaku Nanbu. However, this all changes when the Megalo Box champion Yuuri enters his shabby ring under the guise of just another challenger. Taken out in a single round, Junk Dog is left with a challenge: "If you're serious about fighting me again, then fight your way up to me and my ring." 
 
Filled with overwhelming excitement and backed by the criminal syndicate responsible for his thrown matches, Junk Dog enters Megalonia: a world-spanning tournament that will decide the strongest Megalo Boxer of them all. Having no name of his own, he takes on the moniker of "Joe" as he begins his climb from the very bottom of the ranked list of fighters. With only three months left to qualify, Joe must face off against opponents the likes of which he has never fought in order to meet the challenge of his rival. 
 
(Source: MAL Rewrite)

Shorts included with the Blu-ray releases.

The series is celebrating the 50th anniversary of the original manga. In the new story, a man called JD (Junk Dog) participates in fixed boxing matches in an underground ring in order to live. Today, he enters the ring again, but he encounters a certain person. JD wants to take on a challenge that risks everything.
 
(Source: Anime News Network)

The second season of Megalo Box. 
 
In the end, “Gearless” Joe was the one that reigned as the champion of Megalonia, a first ever megalobox tournament. Fans everywhere were mesmerized by the meteoric rise of Joe who sprung out from the deepest underground ring to the top in mere three months and without the use of gear. Seven years later, “Gearless” Joe was once again fighting in underground matches. Adorned with scars and once again donning his gear, but now known only as Nomad. 
 
(Source: TMS Entertainment)

Joe Yabuki is a troubled young man who runs away from an orphanage. Wandering through the Tokyo slums, he meets former boxing trainer Danpei. Joe is later arrested and goes to a temporary jail where he fights Nishi, his future best friend, ​and leader of a group of hooligans. He and Nishi then go to a juvenile prison miles away from Tokyo. There Joe meets Rikiishi, a former boxing prodigy, and a rivalry develops between them. They face each other in a match in which Rikiishi dominates Joe until the latter hits him with a cross-counter, resulting in both being knocked out. This inspires the other prison inmates to take up boxing. Joe and Rikiishi vow to fight again. 
(Source: Wikipedia)

Joe, a teenage orphan in the slums of the Doya streets, meets Danpei, a homeless, alcoholic ex-boxing coach. Danpei, seeing Joe's boxing talent, decides to train him. When Joe is sent to a terrible juvenile home for petty crimes, he meets Rikiishi who becomes his boxing rival. Danpei arrives at the home to help Joe to train in order to defeat Rikiishi. When Joe decides to seriously pursue boxing, Danpei cannot get a coaching license because of his reputation as a drunk. 
(Source: AnimeNfo)

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