A young man wakes up in a strange room with no memory of who he is or how he got there. His past is lost—and his future belongs to Inferno, a violent crime syndicate. They give him a new name—Zwei—and team him with their top assassin, the enigmatic Ein. She’ll teach Zwei all he needs to know about his new life as an Inferno operative, starting with lesson number one: kill or be killed.
 
(Source: Crunchyroll)

Zwei was an ordinary person, until one day, while walking the streets a night, he witnessed a brutal assassination. He managed to avoid the sniper, a young girl named Ein, but was soon captured, and had the memories of his former life erased. He is spared death only by accepting a condition : to train to become an assassin alongside Ein. Now he must find a way to free himself from this shady world and reclaim his life once again.
 
(Source: Anime News Network)

Mafia is rife in America where assassinations are a regular occurrence on the streets. Inferno, a mysterious company, is behind most of these dealings through the use of their near-invincible human weapon, "Phantom."
One day, a Japanese tourist accidentally witnesses Phantom's latest murder. Desperate to escape, the tourist hides in a secluded building. However, Phantom, revealed to be a young woman named Ein, and the leader of Inferno "Scythe Master" captures the tourist and brainwashes him.
Given the name "Zwei," this once peaceful tourist is now a puppet of Inferno with no memories. Drawn into a world of lies, deceit, and violence, Zwei must fight to survive, hopefully to one day regain his memories and escape from this world where he is constantly on the brink of death.
[Written by MAL Rewrite]

The manga adaptation of Phantom ~Requiem for the Phantom~, authored by Nitroplus and with the art of Masaki Hiragi, is being published in Japan in the magazine Monthly Comic Alive (Media Factory).

Parody opening for a spin-off of Mahou Shoujo Madoka Magica, starring the characters from the upcoming visual novel game SoniComi by Nitro+. 
This was released by Nitro+ as an April fools' prank, complete with an official website announcing a full TV series.

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