In present times, Gods and Demons coexist together with Humans after the door between each of these worlds had opened. Tsuchimi Rin is a normal young high school student attending Verbena Academy, spending his days living peacefully with his childhood friend Kaede. Unexpectedly, one day the King of Gods, the King of Demons and their families move into be Rin's next door neighbors. Apparently the daughter of the Gods, Sia, and the daughter of the demons, Nerine, are both deeply in love with Rin after having met him the past. Along with his playful friendship with upperclassmen Asa and his encounter with the silent but cute Primula, Rin has much on his hands dealing with the affections of each of these girls. Based on the eroge by Navel.

A recap of the Shuffle world, set ten years in the future. Gods, Demons, and Humans freely visit the other worlds as if traveling overseas, and romance is in the air. Demons, Gods, And Humans together have been falling in love and creating new families, breaking down the wall that once seperated them. Past memories are visited by Rin Tsuchimi and the events that occured between him and Lisianthus, Nerine, Kaede, Asa, and Primula.
 
(Source: Anime News Network)

Shuffle! Prologue is a short OVA teaser for the Shuffle! anime series based on the visual novel of the same name. While some of the animation was reused for the first episode of the anime series, most of Shuffle! Prologue is unique animation not repeated in the series, although the story itself is retold. 
(Source: Wikipedia)

Anime description from Froth-Bite: 
The world as we know it was suddenly altered forever when the door for the dimension of the gods and the door of the dimension of the demons suddenly opened up. Ten years later, a boy named Tsuchimi Rin was entrusted with two princesses from those dimensions. Will he be able to keep his sanity while living with his childhood friend Kaede, trying to live a normal school life, and also being a neighbor to both of princesses and their fathers, the mighty dimension Lords? The hearts of those girls are at stake and only Rin has the key to unlock them.

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